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Research - Biomolecular Pharmaceutical Chemistry
The Ross Group has interests in the fields of pharmaceutical and biomolecular chemistry including drug design, peptide/protein biochemistry and biophysics, carbohydrate chemistry, organic synthesis, and dendrimer chemistry. A current focus of our research is Alzheimer’s disease (AD) where we design, synthesise and evaluate inhibitors of beta-amyloid aggregation and inhibitors of the neuronal uptake of toxic amyloid oligomers. Understanding the mechanism of disease is essential for the design of potent and selective drugs, and we are studying the effect of extrinsic factors on the aggregation of beta-amyloid to advance knowledge of the molecular basis of AD. To accomplish these goals, we utilise synthetic chemistry (organic, peptide, carbohydrate, macromolecular) to generate novel molecules that are used a probes and drug candidates in a variety of biophysical screening assays based-on dynamic light scattering, fluorescence spectroscopy, circular dichroism, size-exclusion chromatography, and transmission electron microscopy. Lead molecules progress to advanced biophysical examination, cell-based assays, and animal studies via collaboration with researchers from UQ and overseas.
Please note:Many of our projects are commercially sensitive and cannot be advertised on the web. Please contact Dr Ben Ross to discuss the Group's latest research projects. |
Latest News
14 September 2011, Visiting Scholars: Welcome to Ms Joanne Alexandra and Mr Tham Wai Kin who are pharmaceutical science students from Temasek Polytechnic in Singapore. Joanne and Wai Kin will complete research internships within the Ross Group.
26 May 2011, University Medal: Ms Kara Marcano was awarded a 2010 University Medal for outstanding academic results throughout the BPharm(Hons) program. Kara completed an honours research project in medicinal chemistry within the group. Congratulations Kara.
14 February 2011, Visiting Scholars: Welcome to Ms Christine Nguy and Ms Cynthia Govindjee who are pharmacy students from Paris Descartes University (University of Paris V) in France. Christine and Cynthia will complete research internships within the Ross Group.
20 December 2010, Merit Certificate: PhD candidate Venkatesan Moorthy Rao (Venky) attended the 62nd Indian Pharmaceutical Congress held in Manipal, India from 17-19 December 2010. The Congress attracted over 9000 delegates with 2800 papers selected for presentation. Venky’s oral presentation: “Effect of extrinsic elements on the fibrillisation of amyloid beta protein Abeta(1-28)” was awarded one of only 14 merit certificates for best papers. Congratulations Venky.
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Contact
Dr Ben Ross
Courier address: School of Pharmacy, The University of Queensland, Level 4, Pharmacy Australia Centre of Excellence, 20 Cornwall Street, Woolloongabba, Qld 4102, Australia
Postal address: School of Pharmacy, The University of Queensland, Brisbane, Qld 4072, Australia
Phone: +61 7 334 61888 Fax: +61 7 334 61999
Email:
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This web site was last updated on 26 May 2011. Copyright © 2006-2011 Benjamin P. Ross. Unless stated otherwise, this web site represents only the views of Benjamin P. Ross and not the views of The University of Queensland. Simple site map. |
